CuraBone began from the strong fruitful relationship of Materialise and University of Zaragoza on previous projects. On the one side, M2BE research group counts with internationally acknowledged experience on the development of numerical algorithms for modelling mechanobiological bone behaviour based on multiscale FE simulations and its own mechanobiology lab for cell research. On the other side, Materialise will contribute with their wide expertise on biomedical engineering with numerous modelling technologies to construct patient-specific models from CT images and leader on 3D printing technologies. Both institutions embody the main nucleus of CuraBone’s research and training programme.

Leading institutions

Universidad de Zaragoza (UNIZAR) -founded in 1542- is a continuously growing institution, with more than 40.000 students and more than 2.500 high quality researchers belonging to more than 200 research groups. It is well positioned among National and European Universities. Part of the research activity of UNIZAR is developed within five Research Institutes, the Engineering research one will host CuraBone.

M2BE ( is the research group that will lead CuraBone. Their main research activity is focused in the Computational Mechanobiology field based on FE simulations combining aspects of Mechanical and Biological Engineering. It has physicians among its members to provide clinical and biological expertise to its research.

Materialise's mission is to innovate product development resulting in a better and healthier world through its software and hardware infrastructure and in-depth knowledge of additive manufacturing. At Biomedical Engineering Unit, with Mimics Innovation Suite, we're powering new innovations in biomedical research and helping others make discoveries that save lives. We're also taking patient-specific healthcare to new heights by working closely with experts in the planning and execution of complicated surgical procedures. Our solutions are comprehensive and flexible.

On the basis this balance between Industry and Academia, CuraBone elaborates a wider network of prestigious partner organisations to complement the excellence and expertise of this joint Doctorate Programme. These are partners involved in CuraBone:

Partner organisations

AnyBody Technology (ABT) develops and markets the AnyBody Modeling System™ (AMS), software for musculoskeletal simulation at body-scale. Located in the NOVI science park of Aalborg University, ABT’s technical team consists of nine persons, most holding Ph.D. degrees and all having high-level knowledge and experience in biomechanics, in particular musculoskeletal modeling. The ESR will enter this team and its daily processes as well as their work allow, and they will have rich opportunities to interact with the team members on a daily basis.

The software infrastructure of Aalborg University provides access to a range of technical software including systems for computer-aided design, finite element analysis, computational fluid dynamics and, in particular, musculoskeletal simulation as well as cluster computational environment. The Biomechanics Research Group were the ESr will be hosted is part of the Department of Mechanical and Manufacturing Engineering (M-Tech) but also has close collaboration with the Department of Health Science and Technology (HST).

KU Leuven will be represented by the Biomechanics section of the Faculty of Engineering Science (KUL-BME) and the Human movement biomechanics research group of the Faculty of rehabilitation and human movement science (KUL-HMB). KUL-HMB coordinates MALL (Movement and posture Analysis Laboratory Leuven) consisting of a combination of state of the art laboratories for the analysis of movement., which will provide some ESR equipment to measure 3D segmental movement, reaction forces, and muscle activity. KUL-BME comprises an experimental laboratory for the characterization of mechanical properties of the tissues at the different length scales.

TA Instruments – Waters LLC is an internationally leading company on bioreactor development for regenerative medicine research and product development. In particular, TA Instruments has developed autoclavable bioreactor chambers that attach directly to our test instruments so that loading is applied to soft tissue specimens and global measurements are obtained (e.g., load vs. displacement) throughout the experiment while specimens are fully immersed in fluid. We are continuously expanding our research to enhance our products and our progresses with serve to CuraBone’s training and scientific research.

The Trust is a specialist hospital providing elective orthopaedic surgery and musculoskeletal medical services. It is committed to providing the best possible care, training and research to serve the people of both England and Wales, and beyond. The Robert Jones and Agnes Hunt Orthopaedic Hospital NHS Foundation Trust is an NHS hospital specialising primarily in bone and joint disorders, with specific additional areas of expertise including spinal disorders.

Lozano Blesa Clinic University Hospital is a general University Hospital next to the Faculty of Medicine. Orthopaedic and Trauma Surgery Department has 60 beds, 5 outpatients, four daily operating rooms, 30 staff and 10 residents. It is the second biggest hospital in the city of Zaragoza, and we are referral hospital in two district hospitals. We have hospital sections like Paediatric, Hip, knee, Foot, and Upper Extremity. Our clinical investigation is mainly around Hip arthroplasties, Pelvic Trauma, Knee revisions, and Hip fractures in elderly patients.

Considered one of the most qualified in occupational medicine centres in Spain. This hospital MAZ Mutual has an excellent set of facilities, both in regard to hospital structural aspects such as the technical means of surgery, diagnosis and treatment. Also noteworthy is the high level of qualifications of physicians and health personnel. It also has a Healthcare Ethics Committee (CEA), becoming the first hospital in a Mutual which launched a consultative body of this kind.

The National University of Ireland Galway is ranked among the top 1% of universities in the world. NUIG will be represented by the Mechanobiology and Medical Device Research Group, providing ESRs with experimental techniques to identify the specific mechanosensation and mechanotransduction mechanisms by which bone cells sense mechanical stimuli. This research will be applied to overcome challenges in the field of bone tissue engineering by understanding the role of mechanical stimulation in bone regeneration.

The Robert Jones and Agnes Hunt Orthopaedic Hospital NHS Foundation Trust is an NHS hospital specialising primarily in bone and joint disorders, with specific additional areas of expertise including spinal disorders and metabolic disorders affecting muscular development. It was founded by a visionary nurse and an eminent orthopaedic surgeon early in the last century, whose legacy has been a hospital which continually raises standards, one which pushes boundaries in areas like community-based care, holistic approaches to treatment and multi-disciplinary working between clinicians, physiotherapists and other professionals.



This project has received funding from the European Union's Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 722535.

Web design